Well, the immune system plays a big role. Let’s take a look at how, as person with AD, yours works a little differently.1,2
The immune system is our body’s natural defence, but AD causes yours to be overactive.1 It’s normal for the immune system to respond to threats, like bacteria and viruses, with inflammation.3 This is how the immune system protects the body.
But as a person with AD or eczema, your immune system thinks that some substances, called allergens, are a threat too.3 This means you experience more inflammation than a person without AD.3
You’ve learned about the immune system, but there are other factors that can also play a role in your AD:2,3
Genetics can also play a role in causing AD. Nobody wants to pass down the genetics they don’t like, whether it’s AD, or the nose you hate. But it’s been found that a variation of the gene ‘filaggrin’ results in a damaged skin barrier, which can contribute to AD.
Environmental factors can also play a part in AD too. Things like pollen, animals, and the foods you eat can all be potential triggers for your AD flare-ups.
Changing AD doesn’t happen overnight. But by understanding the role of your immune system, and the fact it isn’t trying to hurt you, you might be able to find more peace with your condition (despite everything it’s put you through). You can work with a dermatologist to proactively manage the underlying causes of AD and work towards long-term control.
Beyond the underlying causes of your AD, you may also find that external factors can trigger flare-ups too.Discover more
It's a simple question, and we've got the simple answer. Let's break down the very basics of AD.Learn more
There are different types of eczema, and atopic dermatitis is one of them. Learn about the differences between each type, and what makes AD stand out.Discover more
Wollina U. Clin Cosmet Investig Dermatol 2017; 10:51–56.
Eyerich K et al. Trends Immunol 2015; 36(12):788–801.
Bieber T. Ann Dermatol 2010; 22(2):125–137.